Subash Ghimire, MD1, Rasmita Budhathoki, MD1, Amlish Gondal, MD1, Tsu Jung Yang, MD1, Michelle Bernshteyn, MD1, Madeline Mylod, MS2, Conor Banta, 3, Vivian Deng, MS2, Noah West, MS2, Sohaib Shabih, MD1, Michael Georgetson, MD1, Thomas McDonald, MD1 1Guthrie Robert Packer Hospital, Sayre, PA; 2Lake Erie College of Osteopathic Medicine, Sayre, PA; 3Geisinger Commonwealth School of Medicine, Sayre, PA
Introduction: World Health Organization (WHO) states that there are no typical older person as physical and mental capacities of older age groups may be like younger. However, with advancing age, comorbid conditions accumulate and may increase the risk of poor outcomes during medical procedures. Studies on outcomes of Endoscopic retrograde cholangiopancreatography (ERCP) on patients of age ≥80 years of age is limited. We performed a study to identify outcomes, risk of complications and associated factors in age ≥80 years undergoing ERCP.
Methods: A single center retrospective review of patients who underwent ERCP procedure was performed. These patients were segregated based on their age (≥80 years or < 80 years). Analysis of comorbid conditions and outcomes were performed using Chi-square test and binominal logarithmic regression model using SPSS v.26
Results: We analyzed 2741 patients, of which 551 (20.1%) were of age ≥80 years. There was similar gender distribution between the 2 groups (43.7% in age ≥80 years vs 44.3% in < 80 yeasrs age group). Smoking was less prevalent in older patients (2.5% vs 16.7%, p< 0.05). COPD prevalence was high in older adults (15.0% vs 11.5%, p=0.02). Diabetes mellitus was similarly more prevalent among older adults (25.0% vs 2.8%, p=0.04), as well as CKD (24.5% vs 11.3%, p< 0.05). Patients with age ≥80 years were frequently hypertensive (73.1% vs 50.1%, p< 0.05). Procedure time was higher for older age group (68.1±22.9 minutes versus 65.8 ± 25.7, P-0.04) as was hospital length of stay (4.0±5.3 versus 3.1±5.0, p=0.02). Logarithmic regression showed post-ERCP pancreatitis was lower in age ≥80 years (OR=0.559, p=.008, 95% CI .362- .861). There was no increased 30-day mortality in ≥80 years age group (OR= 2.281, p=.061, 95% CI .962- 5.405). There was no difference in readmission between the two groups.
Discussion: Post-ERCP pancreatitis (PEP) is lower in patients ≥80 years of age. Although Chi-square analysis shows increased 30-day mortality in age ≥80 years, controlling for confounding variables shows no difference in outcomes. ERCP is a safe procedure to be performed in elderly population.
Note: The table for this abstract can be viewed in the ePoster Gallery section of the ACG 2024 ePoster Site or in The American Journal of Gastroenterology's abstract supplement issue, both of which will be available starting October 27, 2024.
Disclosures:
Subash Ghimire indicated no relevant financial relationships.
Rasmita Budhathoki indicated no relevant financial relationships.
Amlish Gondal indicated no relevant financial relationships.
Tsu Jung Yang indicated no relevant financial relationships.
Michelle Bernshteyn indicated no relevant financial relationships.
Madeline Mylod indicated no relevant financial relationships.
Conor Banta indicated no relevant financial relationships.
Vivian Deng indicated no relevant financial relationships.
Noah West indicated no relevant financial relationships.
Sohaib Shabih indicated no relevant financial relationships.
Michael Georgetson indicated no relevant financial relationships.
Thomas McDonald indicated no relevant financial relationships.
Subash Ghimire, MD1, Rasmita Budhathoki, MD1, Amlish Gondal, MD1, Tsu Jung Yang, MD1, Michelle Bernshteyn, MD1, Madeline Mylod, MS2, Conor Banta, 3, Vivian Deng, MS2, Noah West, MS2, Sohaib Shabih, MD1, Michael Georgetson, MD1, Thomas McDonald, MD1. P4490 - Outcomes of Endoscopic Retrograde Cholangiopancreatography (ERCP) in Octogenarians, Nonagenarians, and Centenarians, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.
